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BSSENTIAL — Balanced Salt Solution 500 mL | Sterile Ophthalmic Irrigating Solution | Agaaz Ophthalmics
Agaaz Ophthalmics · Ophthalmic Surgical Solutions
Sterile Preservative-Free Single-Use

BSSENTIAL Balanced Salt Solution · 500 mL

A sterile, isotonic irrigating solution formulated to mirror the physiological composition of aqueous humour. Designed for precision irrigation during cataract surgery, anterior segment procedures, and vitreoretinal surgery — where fluid clarity and ionic balance are non-negotiable.

~7.5
Physiological pH
~300
mOsm/Kg
500 mL
Volume
6-ion
Electrolyte Formula
pH ~7.5 Physiological
~300 mOsm/Kg Isotonic
121°C Sterilized
BSSENTIAL Balanced Salt Solution 500mL bottle by Agaaz Ophthalmics
Balanced Salt Solution Sterile Irrigating Solution Preservative-Free Single-Use · Single-Patient pH ~7.5 Osmolality ~300 mOsm/Kg 500 mL Polymer Bottle Dual-Port Closure Cataract Surgery Vitreoretinal Surgery Phacoemulsification Anterior Segment Irrigation Agaaz Ophthalmics Balanced Salt Solution Sterile Irrigating Solution Preservative-Free Single-Use · Single-Patient pH ~7.5 Osmolality ~300 mOsm/Kg 500 mL Polymer Bottle Dual-Port Closure Cataract Surgery Vitreoretinal Surgery Phacoemulsification Anterior Segment Irrigation Agaaz Ophthalmics
Ionic Formula

A six-electrolyte formula
matched to aqueous humour

Every ion in BSSENTIAL serves a biological role. Together they recreate the osmotic and ionic environment of the eye's natural fluid — protecting endothelial cells, maintaining tissue integrity, and supporting undisturbed surgical vision.

Sodium Chloride
NaCl
0.64%
Sodium Acetate
C₂H₃NaO₂·3H₂O
0.39%
Sodium Citrate
C₆H₅Na₃O₇·2H₂O
0.17%
Potassium Chloride
KCl
0.075%
Calcium Chloride
CaCl₂·2H₂O
0.048%
Magnesium Chloride
MgCl₂·6H₂O
0.03%
Formulation References
  1. Edelhauser HF et al. Intraocular irrigating solutions and lens clarity. Am J Ophthalmol. 1976.
  2. Glasser DB et al. Toxicity and use of balanced salt solution. Trans Am Ophthalmol Soc. 1985.
  3. BSS® Sterile Irrigating Solution — Alcon Prescribing Information (DailyMed, FDA). 2021.
Product Features

Engineering clarity
into every millilitre

From sterilization protocol to closure design, BSSENTIAL is engineered to support the surgeon at every step — from bottle connection to final aspiration.

Preservative-Free

Zero preservatives eliminates chemical endothelial stress. Safe for prolonged intraocular contact throughout the procedure without cytotoxic risk.

Single-Use Design

Dedicated to one patient, one procedure. Eliminates cross-contamination risk and ensures every surgery begins with a sterile, uncompromised solution.

Physiological Balance

pH ~7.5 and osmolality ~300 mOsm/Kg closely replicate aqueous humour, minimising cellular stress and supporting natural ocular homeostasis during irrigation.

Medical-Grade Polymer Bottle

500 mL container manufactured from medical-grade polymer, transparent for visual inspection, latex-free, and sterilized at 121°C for complete microbial assurance.

Dual-Port Closure

Secure two-port closure system supports both infusion line and venting needle connectivity — designed for dependable, leak-free handling in the operating theatre.

Visual Clarity Verification

Transparent bottle wall allows immediate visual inspection for particulates, discolouration, or clouding before use — an essential sterility check at the point of care.

Physiological Parameters

Engineered to match
the eye's own chemistry

The aqueous humour is not simply water — it is a precisely balanced ionic solution. BSSENTIAL is formulated to approximate its key physicochemical parameters, supporting tissue integrity throughout irrigation.

pH ~7.5
Aqueous humour pH: 7.3–7.6 | BSSENTIAL: ~7.5
Osmolality ~300 mOsm/Kg
Normal osmolality range: 280–310 mOsm/Kg
Na⁺ concentration ~150 mEq/L
Primary cation matching aqueous Na⁺ (~140–150 mEq/L)
Ca²⁺ / Mg²⁺ balance Physiological
Divalent cations essential for endothelial pump function
pH
~7.5
Physiological range
Osmolality
~300
mOsm/Kg isotonic
Volume
500 mL
Per bottle
Sterilization
121°C
Autoclave cycle
Storage
2°–25°C
Ambient cold chain
Ions
6
Na⁺ K⁺ Ca²⁺ Mg²⁺ Cl⁻ Acetate/Citrate
Container
Polymer
Medical-grade, latex-free
Closure
2-Port
Dual-port sealed
Surgical Applications

Indicated across the full
ophthalmic surgical spectrum

BSSENTIAL supports irrigation during procedures where anterior or posterior segment exposure requires continuous, physiologically compatible fluid management for the duration of surgery (expected maximum: <60 minutes).

Phacoemulsification

Continuous anterior chamber irrigation during ultrasonic lens fragmentation. Maintains chamber depth, cools phaco tip, and protects the endothelium from mechanical and thermal stress.

ECCE / Manual Cataract Surgery

Extraocular and intraocular irrigation during extracapsular cataract extraction. Maintains the surgical field, supports anterior chamber stability, and aids cortex removal.

Anterior Vitrectomy

Anterior segment vitreous management requiring continuous infusion. Maintains positive pressure and clear surgical visibility during vitreous prolapse procedures.

Corneal Transplantation

Graft and recipient bed irrigation during penetrating keratoplasty (PK) and lamellar procedures. Maintains donor endothelial cell viability during preparation and placement.

Glaucoma Surgery

Irrigation during trabeculectomy, tube shunt implantation, and goniotomy procedures. Supports the anterior chamber during paracentesis and controlled fluid exchange.

Extraocular Surface Irrigation

Conjunctival lavage, corneal surface rinsing, and operative field washout. The isotonic formula prevents osmotic trauma to the ocular surface epithelium.

Safety & Storage

Important safety
information

BSSENTIAL is a surgical irrigating solution. Correct use, storage, and disposal are essential for patient safety and product efficacy.

⚠️

Not for Injection or IV

BSSENTIAL is strictly for ophthalmic irrigation use. It must never be administered by injection or intravenous infusion. Do not confuse with parenteral fluids.

🔍

Pre-Use Inspection

Inspect the bottle before every use. Do not use if the solution is discoloured, contains particulates, the seal is broken, or the container shows any damage.

🚫

Single Patient Only

Contents must not be used for more than one patient. Discard any remaining solution after the procedure. Multiple-patient use risks infection and cross-contamination.

🌡️

Storage: 2°–25°C

Store at controlled room temperature between 2°C and 25°C. Protect from freezing. Do not use a bottle that has been frozen or exposed to excessive heat.

⏱️

Procedure Duration

BSSENTIAL is indicated for procedures with an expected intraocular perfusion duration of less than 60 minutes. For longer procedures, consider BSS-Plus class solutions with additional metabolic support.

Diabetic Patients

Use with caution in diabetic patients undergoing vitrectomy. Isotonic BSS-class solutions without glucose supplementation may contribute to intraoperative lens changes in this population.

Frequently Asked

Clinical questions
answered

Practical answers for surgeons, theatre nurses, and procurement teams.

Ask a Question
What is balanced salt solution used for in ophthalmic surgery?
BSS is a sterile isotonic irrigation fluid used during ophthalmic surgery to maintain anterior chamber depth, hydrate tissue surfaces, remove debris from the surgical field, and replicate the physiological environment of aqueous humour. It is used in cataract surgery, anterior and posterior vitreoretinal procedures, corneal transplantation, and glaucoma surgery.
What is the composition of BSSENTIAL?
Each mL contains: NaCl 0.64%, KCl 0.075%, Calcium chloride dihydrate 0.048%, Magnesium chloride hexahydrate 0.03%, Sodium acetate trihydrate 0.39%, Sodium citrate dihydrate 0.17%. pH adjusted to ~7.5; osmolality ~300 mOsm/Kg. Preservative-free.
Is BSSENTIAL safe for intraocular irrigation?
Yes. BSSENTIAL is formulated for both extraocular and intraocular irrigation. It is preservative-free, isotonic, and pH-balanced to minimise endothelial toxicity and tissue stress during intraocular procedures expected to last less than 60 minutes.
Can BSSENTIAL be used for injection or IV infusion?
No. BSSENTIAL must never be used for injection or intravenous infusion. It is exclusively an ophthalmic surgical irrigating solution and is not intended for systemic use under any circumstances.
How should BSSENTIAL be stored?
Store at 2°C to 25°C. Protect from freezing and excessive heat. Do not use if the seal is compromised, the solution is cloudy, or the container is damaged. Discard unused contents after single patient use.
How do I order BSSENTIAL for my hospital or clinic?
Contact Agaaz Ophthalmics at info@agaaz.life or via WhatsApp at +91 98241 64173. We supply directly to hospitals, eye care centres, and regional distributors globally. Export documentation and regulatory support available for international orders.

Source BSSENTIAL
for your surgical team

Available for direct procurement, hospital tender supply, and international distributor partnerships. Contact the Agaaz Ophthalmics team to discuss pricing, minimum quantities, and regulatory documentation.

BSSENTIAL is a sterile balanced salt solution indicated for ophthalmic irrigation use only. Not for injection or intravenous infusion. Single-patient use — discard unused contents. Store at 2°–25°C. For professional surgical use by trained ophthalmic personnel only. This page is for informational purposes and does not constitute medical advice. Always refer to the product package insert for full prescribing information, contraindications, and warnings.