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INTRAOCULAR SURGICAL DYE
Capsule StainSterile15+ Countries

OP‑BLUE Trypan Blue Ophthalmic Solution

Capsule-staining dye engineered for crisp visualisation of the anterior capsule, supporting controlled capsulorhexis in mature and challenging cataracts. Trusted by surgeons in 15+ countries.

0.06%
Trypan Blue
1.5 ml
Export Pack
15+
Countries Served
Enquire for Pricing Download Brochure
ANTERIOR CAPSULE STAINING
OP-BLUE trypan blue ophthalmic solution 1.5 ml vial
Crisp VisibilityCapsule Contrast
15+ CountriesGlobally Trusted
1.5 mlExport Pack
Trypan Blue 0.06%Capsule StainingCapsulorhexis SupportMature CataractsWhite Cataracts1.5 ml Export Pack15+ CountriesSterile Single-UseTrypan Blue 0.06%Capsule StainingCapsulorhexis SupportMature CataractsWhite Cataracts1.5 ml Export Pack15+ CountriesSterile Single-Use

Engineering anatomy

Stain the edge you need to see.

In a white cataract the capsule is hard to see against the lens behind it. Follow the four steps of the technique on a model eye: air in, dye on, rinse clear, and the blue capsule edge stays in view for the whole capsulorhexis.

Trypan blue 0.06% on the anterior capsuleBlunt cannula and capsulorhexis edgeAir bubble in the anterior chamberSchematic, after the page's application technique. Strength (trypan blue 0.06% w/v) and pack sizes are product data; the model eye, cannula, volumes and timing are illustrative. This is not instructions for use: follow the IFU, and technique is the surgeon's.

Generic
Trypan blue ophthalmic solution
Strength
0.06% w/v
Packs
1.5 mL export; 1 mL India only
Use
Anterior capsule staining; ERM / ILM in vitreoretinal surgery
Format
Sterile, single use
CLINICAL PURPOSE

Designed to make the capsule edge unmistakable

OP‑BLUE stains the anterior lens capsule so the capsulorhexis edge stays visible during mature white cataracts, poor red reflex cases, and narrow pupils: situations where an unstained capsule is hard to tear cleanly.

Capsular Visibility

Improves anterior capsule contrast so the tear edge stays clear, visible, and controllable throughout capsulorhexis.

Mature Cataracts

Supports confident capsulorhexis in mature white cataracts, poor red reflex cases, and eyes with reduced capsular landmarks.

Workflow Integration

Easy to place within existing cataract protocols without disrupting OT rhythm, as a single step before capsulorhexis.

Vitreoretinal Use

Also used to stain epiretinal membranes (ERM) and internal limiting membranes (ILM) during vitreoretinal procedures.

PACK SIZES

Two presentations.
One surgical standard.

1.5 ml is the export presentation. 1 ml is supplied in India only.

OP-BLUE 1.5 ml

OP‑BLUE 1.5 ml · Export

Trypan Blue 0.06% — the export presentation, standard volume for routine cataract workflows.

OP-BLUE 1 ml

OP‑BLUE 1 ml · India

Supplied in India only; not available for export.

APPLICATION TECHNIQUE

How to use trypan blue for capsule staining.

A standardized technique for consistent capsular visualisation across routine and complex cataract cases.

1

Air Bubble

Inject an air bubble into the anterior chamber to minimize dilution of the dye by aqueous.

2

Apply Dye

Carefully apply OP‑BLUE onto the anterior lens capsule using a blunt cannula. Staining occurs on contact.

3

Irrigate

Irrigate the anterior chamber with balanced salt solution to remove all excess dye.

4

Capsulorhexis

Proceed with capsulorhexis. The stained capsule edge remains clearly visible throughout the procedure.

SPECIFICATIONS

Key parameters at a glance.

For the complete technical table and artwork, use the brochure download.

Brand
OP‑BLUE
Capsule dye
Generic
Trypan Blue
Ophthalmic solution
Strength
0.06%
w/v
Export pack
1.5 ml
Sterile single-use
PUBLISHED RESEARCH

What the published literature says about trypan blue capsule staining

The clinical case for this product category does not rest on our own material. The studies below are independent, peer-reviewed and indexed in PubMed, and they cover trypan blue capsule staining as a subject. Each entry links to its PubMed record so the primary source can be read in full.

  1. Systematic ReviewOutcomes of paediatric cataract surgery with and without the use of trypan blueAbdulRahman A et al. (2022) · Tropical medicine & international health : TM & IH · PMID 35859347
  2. Randomized Controlled TrialThe effects of trypan blue use on the corneal endothelium during cataract surgery in patients with pseudoexfoliation syndrome (PEX)Ucar F et al. (2021) · Cutaneous and ocular toxicology · PMID 34342246
  3. Randomized Controlled TrialTrypan blue injection into the capsular bag during phacoemulsification: initial postoperative posterior capsule opacification resultsSharma P & Panwar M (2013) · Journal of cataract and refractive surgery · PMID 23499069

Independent peer-reviewed publications indexed in PubMed. Listed as clinical background on the molecule and device class; they are not studies of Agaaz products and imply no endorsement.

Further reading

FREQUENTLY ASKED QUESTIONS

Common questions about
trypan blue and OP‑BLUE.

What is trypan blue ophthalmic solution used for?
Trypan blue ophthalmic solution 0.06% is a selective tissue staining agent used during cataract surgery to stain the anterior lens capsule. It improves capsular visibility, making capsulorhexis easier and more controlled, especially in mature white cataracts, eyes with poor red reflex, corneal scarring, or narrow pupils. It is also used to stain epiretinal and internal limiting membranes during vitreoretinal surgery.
How is OP‑BLUE applied during cataract surgery?
An air bubble is injected into the anterior chamber to minimize dilution. OP‑BLUE is then carefully applied onto the anterior lens capsule using a blunt cannula. Staining is achieved on contact with the capsule. Excess dye is irrigated from the anterior chamber with balanced salt solution before proceeding with capsulorhexis.
What pack sizes is OP‑BLUE available in?
OP‑BLUE 1.5 ml is the export presentation. OP‑BLUE 1 ml is supplied in India only. Both are sterile, single-use and contain trypan blue 0.06% w/v ophthalmic solution.
Who manufactures OP‑BLUE and where is it exported?
OP‑BLUE is manufactured by Agaaz Ophthalmics in India. It is one of Agaaz's most widely used products and is trusted by surgeons in 15+ countries across Asia, Africa, Latin America, and other international markets. It is Agaaz's best-selling product both domestically and internationally.
Is trypan blue safe for intraocular use?
Trypan blue 0.06% has been used extensively worldwide for anterior capsule staining. Studies show no cytotoxic effects on corneal endothelial cells at surgical concentrations. The dye does not penetrate the capsule and excess is removed by irrigation. Important: trypan blue should not be used with non-hydrated hydrophilic acrylic IOLs, as the lens may absorb the dye.

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