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OP‑VISC & PURE‑VISC — HPMC Ophthalmic Viscoelastics | Agaaz Ophthalmics
OPHTHALMIC VISCOELASTICS

OP‑VISC & PURE‑VISCHPMC Viscoelastics • Ready-to-Use Syringes

Two viscosity grades of the same HPMC family, each suited to a different moment in surgery. Ask what you need the OVD to do right now: to coat, spread and flow, reach for OP‑VISC. To create and hold space, reach for PURE‑VISC.

~5000 cps
OP‑VISC
~9000 cps
PURE‑VISC
2 & 3 ml
Export Syringes
GMP Certified Manufacturing CDSCO Licensed Medical Device Manufacturer
VISCOSITY FLOW
OP-VISC HPMC viscoelastic prefilled syringe
OP‑VISC~5000 cps Flow
PURE‑VISC~9000 cps Hold
Syringe FormatReady-to-Use
OP‑VISC ~5000 cpsPURE‑VISC ~9000 cpsHPMC ViscoelasticChamber StabilityEndothelial ProtectionSterile Single-UseExport: 2 ml & 3 mlOP‑VISC ~5000 cpsPURE‑VISC ~9000 cpsHPMC ViscoelasticChamber StabilityEndothelial ProtectionSterile Single-UseExport: 2 ml & 3 ml

Engineering anatomy

Same load, two speeds.

Put the same weight on two identical syringes, one of OP-VISC (~5000 cps) and one of PURE-VISC (~9000 cps). The thinner grade flows faster and spreads; the thicker one moves at about 0.56 of the speed and holds its shape. That is the whole difference between coating and space-keeping, in one press.

SAME LOADOP-VISCPURE-VISC
HPMC viscoelasticSyringe barrels and cannulas (generic)Equal weights on each plungerSchematic. The working viscosities are the published ~5000 and ~9000 cps. Treating both as Newtonian at this rate (HPMC solutions are only mildly shear-thinning), equal force through equal cannulas gives flow in inverse proportion to viscosity: 5000 / 9000 = 0.56. Both grades are shown in glass prefilled syringes; cannula, drop sizes and times are illustrative. Which grade suits which step is the surgeon's call.

Generic
HPMC (hydroxypropyl methylcellulose)
Strength
HPMC 2%, both grades
OP-VISC
~5000 cps · flow & coating
PURE-VISC
~9000 cps · space & support
Rate ratio, same load
0.56 (Newtonian estimate)
Use
Cataract surgery OVD
PURPOSE & HANDLING

Chamber stability and
confident surgical flow.

Both viscoelastics maintain anterior chamber depth, protect intraocular structures, and support confident surgical manipulation — the choice is the viscosity feel your surgeons prefer.

Chamber Maintenance

Maintains stable anterior chamber depth throughout surgical manoeuvres for confident, controlled procedures.

Two viscosity profiles

OP‑VISC (~5000 cps) for smooth flow in routine cases. PURE‑VISC (~9000 cps) for firmer space creation in demanding work.

Endothelial Protection

HPMC coats and protects the corneal endothelium during phacoemulsification and IOL implantation.

Ready-to-Use Syringe

Supplied in a ready-to-use syringe — no preparation, consistent delivery. The PFS presentation is supplied in India only.

STEP-BY-STEP DECISION GUIDE

Which one fits which step of surgery?

Viscosity behaves differently at each stage of cataract surgery. This is a rheology-based reading of the published surgical sequence, not a claim that either product is universally superior — always confirm against your own technique and case.

STEP 01

Entering & forming the chamber

More logical choice: PURE‑VISC

Greater low-shear resistance supports space maintenance while the eye is first entered.

STEP 02

Capsulorhexis

More logical choice: PURE‑VISC

The higher-viscosity product tends to hold a firmer, more stable operating field.

STEP 03

Hydrodissection / viscodissection

More logical choice: Depends on technique

For true viscodissection, OP‑VISC is more logical — it should enter tissue planes more readily.

STEP 04

Phacoemulsification

More logical choice: Often OP‑VISC

Its lower viscosity is formulated to spread over the endothelium and around instruments where coating is the priority.

STEP 05

Cortex removal

More logical choice: Either

OP‑VISC for spreading and access; PURE‑VISC where greater chamber or bag stability is preferred.

STEP 06

Inflating the capsular bag

More logical choice: PURE‑VISC

Higher viscosity is formulated to better maintain the expanded bag before IOL insertion.

STEP 07

IOL insertion

More logical choice: PURE‑VISC for bag support

For cartridge lubrication specifically, OP‑VISC’s lower resistance may help — subject to your own compatibility check.

STEP 08

OVD removal

More logical choice: Cannot be determined from viscosity alone

Removal depends on cohesion, retention, polymer behaviour and aspiration technique, not viscosity alone.

HOW VISCOELASTICS WORK

How HPMC viscoelastics
support cataract surgery.

HPMC-based OVDs are established anterior-segment surgical adjuncts that coat surfaces, maintain space, and protect tissue — viscosity grade shifts which of those roles a given formulation favours.

STEP 01

Chamber Injection

HPMC viscoelastic is injected into the anterior chamber, immediately creating a stable working space.

STEP 02

Surface Coating

Their HPMC formulation is designed to coat the corneal endothelium and surrounding structures, forming a protective layer during phacoemulsification.

STEP 03

Space Maintenance

Maintains anterior chamber depth throughout the procedure, preventing collapse and supporting confident manipulation.

STEP 04

Easy Removal

At close of surgery, the viscoelastic is aspirated. HPMC is designed for straightforward removal from the anterior chamber.

SPECIFICATIONS

Key parameters at a glance.

Brand
OP‑VISC / PURE‑VISC
HPMC Viscoelastics
Generic
HPMC
Hydroxypropyl Methylcellulose
Strength
~5000 / ~9000 cps
Two viscosity profiles
Use
Dual Viscosity
Cataract surgery OVD
PUBLISHED RESEARCH

What the published literature says about hpmc viscoelastics in cataract surgery

The clinical case for this product category does not rest on our own material. The studies below are independent, peer-reviewed and indexed in PubMed, and they cover hpmc viscoelastics in cataract surgery as a subject. Each entry links to its PubMed record so the primary source can be read in full.

  1. Systematic ReviewSafety profile of long-term intraocular ophthalmic viscoelastic devices: a systematic reviewKhalil R et al. (2026) · The British journal of ophthalmology · PMID 41558833
  2. Randomized Controlled TrialA clinical comparison between DisCoVisc and 2% hydroxypropylmethylcellulose in phacoemulsification: a fellow eye studyEspíndola RF et al. (2012) · Clinics (Sao Paulo, Brazil) · PMID 23018304
  3. Randomized Controlled TrialIntraocular pressure after phacoemulsification using hydroxypropyl methylcellulose and sodium hyaluronate as viscoelasticsWaseem M et al. (2007) · Journal of Ayub Medical College, Abbottabad : JAMC · PMID 17867479

Independent peer-reviewed publications indexed in PubMed. Listed as clinical background on the molecule and device class; they are not studies of Agaaz products and imply no endorsement.

FREQUENTLY ASKED QUESTIONS

Common questions about
HPMC viscoelastics.

What is HPMC ophthalmic viscoelastic used for?
HPMC viscoelastic is used during cataract surgery to maintain anterior chamber depth, protect corneal endothelium, facilitate IOL implantation, and create working space. HPMC OVDs are generally described in the literature as having dispersive-leaning coating behaviour, though the precise classification depends on each product’s own rheological testing.
What is the difference between OP‑VISC and PURE‑VISC?
OP‑VISC has ~5000 cps for smooth flow and easy removal. PURE‑VISC has ~9000 cps for firmer space creation. Both are HPMC-based, in ready-to-use syringes.
Which presentations are supplied for export?
For export: OP‑VISC in 2 ml and 3 ml, PURE‑VISC in 3 ml, in ready-to-use syringes. The PFS presentations of both are supplied in India only.
Who manufactures these viscoelastics?
Both are manufactured by Agaaz Ophthalmics, an Indian manufacturer and global exporter of ophthalmic surgical products.

Tell us which viscosity
your surgeons prefer.

OP‑VISC (~5000 cps), PURE‑VISC (~9000 cps), or both? Share your country and volumes for pricing and documentation.